During in vitro gametogenesis, researchers create gametes (sperm and egg cells) from induced pluripotent stem cells, which are unspecialized cells converted from body tissue that researchers can then manipulate into, say, blood cells or neurons. It’s a new variation on what scientists call in vitro gametogenesis. The new announcement marks the first time that researchers have managed to turn a stem cell from an adult male mouse into an egg. Katsuhiko Hayashi, a stem cell biologist at Kyushu University in Japan, presented the new research on March 8 at the Third International Summit on Human Genome Editing at the Francis Crick Institute in London. For the first time, researchers have created mice with two biologically male parents by manipulating the chromosomes inside a stem cell.
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